Ulrike Fuchs How Can The Latest Developments in Beam Shaping Improve Microscopy?
asphericon GmbHJena, Germany
Founded in 2001, asphericon is one of the technology leaders in the field of aspheric optics and systems. By combining a worldwide unique CNC control technology with high-end manufacturing processes, asphericon routinely achieves unique levels of dimensional precision for optical components, assemblies and systems. The latest manufacturing technologies, continually evolving proprietary control software, world-class metrology equipment, and highly qualified employees ensure that asphericon can provide more than 750 customers worldwide with innovative solutions. asphericon assists its customers from the initial optical design, through manufacturing and coating, precision metrology, optical characterization to the assembly of optical modules to complete ready-made systems - everything at a space approved quality level.
The microscope is an essential tool in many areas of scientific research. In this video, ULRIKE FUCHS explains how the latest developments in laser technology can significantly improve microscopy. Focusing on fluorescence microscopy, Fuchs demonstrates the advantages of using a laser with a “top hat” shaped beam distribution in place of the standard Gaussian beam distribution. Delivering striking improvements in areas including photo bleaching and high throughput stitching, the research also has important implications for common and stimulated emission depletion (STED) microscopy.
LT Video Publication DOI: https://doi.org/10.21036/LTPUB10783
Flat-field Illumination for Quantitative Fluorescence Imaging
- Ian Khaw, Benjamin Croop, Jialei Tang, Anna Moehl, Ulrike Fuchs and Kyu Young Han
- Optics Express
- Published in 2018