Matthew Larkum What is Memory and How Does it Function at the Cellular Level?
© Heike Zappe/ HU Berlin
Humboldt University of Berlin (Humboldt-Universität zu Berlin)Berlin
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The SFB 1315 "Mechanisms and disturbances in memory consolidation: from synapses to systems" is a DFG funded Humboldt University project.
Vital steps have been taken in recent years in our understanding of how the cerebral cortex functions at the cellular level. In this video, MATTHEW LARKUM analyzes the role that memory plays in this context. Employing techniques including electrical and optical recordings as well as chemogenetics in experiments with live animals, Larkum’s lab has demonstrated that the medial temporal lobe projects to layer one of the neocortex and that this is central to the ability to learn. With several subsidiary findings casting further light on how memory functions, Larkum’s groundbreaking research promises to continue to reveal secrets about what occurs during memory storage at the cellular level.
LT Video Publication DOI: https://doi.org/10.21036/LTPUB10894
Perirhinal Input to Neocortical Layer 1 Controls Learning
- Guy Doron, Jiyun N. Shin, Naoya Takahashi, Moritz Drüke, Christina Bocklisch, Salina Skenderi, Lisa de Mont, Maria Toumazou, Julia Ledderose, Michael Brecht, Richard Naud and Matthew E. Larkum
- Published in 2020