Arno Villringer How Can Functional Magnetic Resonance Imaging Help Detect, Visualize, and Treat Strokes?
© Maximilian Dörrbecker
Max Planck Society
"The Max Planck Society is Germany's most successful research organization. Since its establishment in 1948, no fewer than 18 Nobel laureates have emerged from the ranks of its scientists, putting it on a par with the best and most prestigious research institutions worldwide. The more than 15,000 publications each year in internationally renowned scientific journals are proof of the outstanding research work conducted at Max Planck Institutes – and many of those articles are among the most-cited publications in the relevant field." (Source)
Max Planck Institute for Human Cognitive and Brain Sciences
The aim of the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig is to investigate human cognitive abilities and brain processes. The main focus of the research is on the neuronal basis of higher functions of the brain such as speech, music, and action. To this end, the scientists’ primary interest focuses on how these are perceived, processed, planned, and generated, as well as how perception and generation influence each other. They also investigate the plastic changes to the brain after strokes, and how these affect different cognitive abilities. The Department of Neurophysics, which was established in early 2007, is specifically concerned with the use and development of imaging methods for the neurosciences. (Source)
Stroke is one of the most frequent neurological disorders, befalling over 250.000 persons each year in Germany alone. The research underlying this video explores the role of non-invasive methods for stroke diagnosis and therapy. The use of functional Magnetic Resonance Imaging (fMRI), which produces image-signals on the basis of the oxygen-concentration in the blood, allows for the detection of increased or decreased activity in the brain. ARNO VILLRINGER explains how this method helps detect affected networks of the brain in the acute phase and enables a tracking progress in the chronic phase of a stroke: The networks of disturbed blood flow in the brain correspond to changes in the neurological functions of the patient. By identifying and visualizing the affected areas non-invasively a continuous monitoring of the patient and a targeted application of treatments, e.g. magnetic stimulation or drugs, is possible and is already tested in clinical studies.
LT Video Publication DOI: https://doi.org/10.21036/LTPUB10351
Identifying the Perfusion Deficit in Acute Stroke With Resting-state Functional Magnetic Resonance Imaging
- Y. Lv, D. S. Margulies, R. C. Craddock, X. Long, B. Winter, D. Gierhake, M. Endres, K. Villringer, J. Fiebach and A. Villringer
- Annals of Neurology
- Published in 2013